Laser-assisted Hatching(LAH)
The advent of the laser has allowed the development of precision techniques to manipulate embryos for enhanced fertility. Laser-assisted hatching can turn around a history of failure for embryos to implant themselves in the uterine wall.
Assisted hatching is used to help the embryo hatch from its protective outer shell, the zona pellucida, and promote implantation in the uterine wall after embryo transfer. Laser-assisted hatching (LAH) with the LYKOS® uses a highly focused infrared laser beam to remove the zona pellucida in very precise increments. Prior to the clinical availability of the lasers, only mechanical or chemical methods could be used for assisted hatching of human embryos in clinical settings. Laser-assisted hatching requires less handling of the embryo than these other assisted hatching methods. Also, laser-assisted hatching is faster than the other methods and, therefore, the embryo spends less time outside the incubator.
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Indications for Indications for LAH
Age
Women over 37 years old
Hormonal Status
Women with an elevated baseline level of FSH
Embryo Quality
Women with poor prognosis embryos, including conditions such as a thick zona pellucida, slow cell division rate, or high cell fragmentation
IVF Attempts
Women who have failed 1 or more IVF cycles
Frozen Embryos
Women using frozen/thawed embryos, which may have hardened zona pellucida
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